Chemosensors, Free Full-Text

Por um escritor misterioso

Descrição

Alcoholic beverages contaminated with scopolamine (SCP) are often employed for criminal purposes due to their sedative effect. The determination of the residual levels of SCP in body fluids (e.g., urine) can help to track possible victims of induced ingestions. Biological sample analysis usually requires a preconcentration step to enhance their detectability and to provide sample clean-up. Molecularly imprinted polymers (MIPs) in lieu of conventional solid sorbents represent an enhancement of selectivity, due to their specific recognition sites. Additionally, the adaptation of the solid-phase extraction (SPE) cartridge into a disposable pipette tip extraction (DPX) contributes to the miniaturization of the sample preparation step. Herein, an analytical method for the determination of SCP in synthetic urine samples via the integration of molecularly imprinted solid-phase extraction (MISPE) with DPX as a preconcentration step prior to capillary electrophoresis analysis (also known as MISPE-DPX-CE) is presented. The extraction and elution steps were optimized using a factorial design. Using the optimized conditions, a preconcentration factor of 20 was obtained, leading to a working range of 0.5–6 µM with LOD of 0.04 µM and repeatability of 6.4% (n = 7) and adequate recovery values (84 and 101%) The proposed MISPE-DPX-CE approach was successfully applied to selective extraction, preconcentration, and determination of SCP in synthetic urine samples.
Chemosensors, Free Full-Text
A supramolecular cucurbit[8]uril-based rotaxane chemosensor for
Chemosensors, Free Full-Text
Chemosensors An Open Access Journal from MDPI
Chemosensors, Free Full-Text
Azine based fluorescent rapid off-on chemosensor for detecting
Chemosensors, Free Full-Text
Chemosensors, Free Full-Text
Chemosensors, Free Full-Text
Driver Fingerprint Solution X105 - Colaboratory
Chemosensors, Free Full-Text
Inhibiting proton interference in PET chemosensors by tuning the
Chemosensors, Free Full-Text
Naphthoquinone-Dopamine Linked Colorimetric and Fluorescence
Chemosensors, Free Full-Text
Frontiers Recent Progress in Fluorescent Probes For Metal Ion
Chemosensors, Free Full-Text
Frontiers Facile Synthesis of Water-Soluble Rhodamine-Based
Chemosensors, Free Full-Text
Frontiers A Colorimetric Chemosensor Based on a Nozoe Azulene
Chemosensors, Free Full-Text
Quinoline based thiosemicarbazones as colorimetric chemosensors
de por adulto (o preço varia de acordo com o tamanho do grupo)