Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
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Descrição

A molecular switch between mammalian MLL complexes dictates

MLL fusion proteins as targets for small molecule inhibition

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression

A molecular switch between mammalian MLL complexes dictates

Molecules, Free Full-Text

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic

A Box of Chemistry to Inhibit the MEN1 Tumor Suppressor Gene

Leukemogenesis via aberrant self‐renewal by the MLL/AEP‐mediated
Trithorax and polycomb cooperation in MLL fusion acute leukemia

Menin-MLL inhibitor MI-2 Epigenetic Reader Domain Inhibitor

IJMS, Free Full-Text

Challenges and opportunities in targeting the menin–MLL

Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
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