Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study - The Lancet Oncology
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Study inclusions and exclusions. Numbers of patients included (left)
Circulating cell-free DNA-based multi-cancer early detection: Trends in Cancer
Multimodal cell-free DNA whole-genome analysis combined with TET-Assisted Pyridine Borane Sequencing is sensitive and reveals specific cancer signals
The Potential Value-Based Price of a Multi-Cancer Early Detection Genomic Blood Test to Complement Current Single Cancer Screening in the USA
Triaging suspected cancer with a multi-cancer early detection blood test - The Lancet Oncology
The Lancet Oncology Publishes Results from SYMPLIFY, The First Prospective Study of a Multi-Cancer Early Detection Test in a Symptomatic Patient Population - GRAIL
Multicancer early detection test: Preclinical, translational, and clinical evidence–generation plan and provocative questions - Kisiel - 2022 - Cancer - Wiley Online Library
Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study - The Lancet Oncology
VisualAbstract: Multicancer early detection blood tests show promise but warrant further clinical evaluation
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of Oncology
The presenting symptom signatures of incident cancer: evidence from the English 2018 National Cancer Diagnosis Audit
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